Avastin Binding Assays

BioOutsource has extensive experience in the development, optimization and validation of a wide range of different types of binding assays and immunoassays and offers GCP, GLP and cGMP-compliant testing services in compliance with EMA and FDA guidelines to support the biopharmaceutical industry.
Using this experience, we have created a range of off-the-shelf binding assays, including Avastin C1q binding assay and affinity measurements using the Avastin VEGF binding assay, Avastin FcRn binding assay and Avastin Fc-Gamma Receptor binding assays to support characterization and biosimilarity studies.

Binding assays are employed to study a number of different features of Avastin (bevacizumab) and play a vital role in the development process and characterization and comparability studies by measuring the binding of Avastin to VEGF as well as C1q, the Fc Gamma Receptors (FcR) and the neonatal Fc Receptor (FcRn). BioOutsource offers a comprehensive range of off-the-shelf generic binding methods to support the characterization of Avastin (bevacizumab) and performance of extensive comparability studies:

These methods have been developed using different platforms including ELISA, Electrochemiluminescence (MSD) or Surface Plasmon Resonance and can be performed with a variety of different reporting mechanisms including affinity, on and off rates as well as relative binding using a totality of data evaluation approach to provide you with comprehensive, industry-leading comparability reports to understand all aspects of the performance of your Avastin molecule.

BioOutsource offers cost-effective solutions to develop custom methods that are not currently in our portfolio please contact us to find out more.

 

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