Cell Line Development

News: Fast Track – DNA to RCB in 14 weeks

Sartorius is a leading provider of cell line development and upstream process development services for large-scale protein production of biopharmaceuticals in mammalian (CHO) cells. The cell line development is performed based on the CellcaCHO Expressions Platform. A unique cell line development technology platform made up of 4 key components:

Together they deliver high yielding, stable cell lines and robust, simple, fed-batch processes for the biopharmaceutical market. The CellcaCHO Expression Platform is an easily accessible, scalable and robust system that takes your product from DNA to RCB in just 14 weeks.

CellcaCHO Expression Platform

CellcaCHO Expression Platform

Track Record

Since inception, Sartorius Stedim Cellca has delivered over 100 CHO cell lines expressing various biologics, which have progressed to clinical trials and market approval including:

  • mAbs (IgG1, IgG4, IgG2)
  • Fc-fusion proteins
  • Fab-related products
  • Bispecific antibodies
  • Biosimilars antibodies
  • Other recombinant and complex proteins

We have extensive experience in custom cell line development projects, including difficult to express proteins.

The CellcaCHO Expression Platform consistently delivers production processes with titres of 3 g/L or more, which is evidenced in our successful track record:

Track Record CellcaCHO

 

Customers First

As well as the unique technology platform, we consider our customers as our greatest asset. To achieve our purpose of providing high-producing, stable cell lines to our customers, our dedicated cross-functional project teams work meticulously on the successful realisation of each project. We believe in a continuous dialogue between the customer and project team to ensure a steady effective flow of information during all project stages. Thereby, we guarantee competent responsiveness on all levels and manage your cell line and process development program accordingly.

Our satisfied loyal customers have repeatedly recommended our cell line development and upstream process development services to their peers, enabling continuous growth of our global customer base, which currently includes about 60 big and small pharma or biotech companies from Europe, the USA, Asia, and Australia with a customer retention rate of more than 80%. Industry references available on request.

Contact our experts to discuss our cell line development services today.

Contact us

 

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