Cell Line Development

News: First CellcaCHO™ cell line has advanced to MARKET APPROVAL!!

Sartorius Stedim Cellca is a leading provider of cell line development and upstream process development services for large-scale protein production of biopharmaceuticals in mammalian (CHO) cells. For this purpose, Cellca has devised a unique cell line development technology platform made up of 4 key components:

Together they deliver high yielding, stable cell lines and robust, simple, fed-batch processes for the biopharmaceutical market. The CellcaCHO Expression Platform is an easily accessible, scalable and robust system that takes your product from DNA to RCB in just 4 months.

CellcaCHO Expression Platform

CellcaCHO Expression Platform

Track Record

Since inception, Sartorius Stedim Cellca has delivered over 76 CHO cell lines expressing various biologics, which have progressed to clinical trials and market approval including:

  • mAbs (IgG1, IgG4, IgG2)
  • Fc-fusion proteins
  • Fab-related products
  • Bispecific antibodies
  • Biosimilars antibodies

We have extensive experience in custom cell line development projects, including difficult to express proteins.

The CellcaCHO Expression Platform consistently delivers production processes with titres of 3 g/L or more, which is evidenced in our successful track record:


 2.0 g/L3.0 g/L4.0 g/L5.0 g/L6.0 g/L7.0 g/L8 g/L
Pre-clinic & Phase 116292012811
Phase 21-1-1--
Phase 3-1-1---
Market Approval1------

Customers First

As well as the unique technology platform, we consider our customers Cellca’s greatest asset. To achieve our purpose of providing high-producing, stable cell lines to our customers, our dedicated cross-functional project teams work meticulously on the successful realisation of each project. We believe in a continuous dialogue between the customer and project team to ensure a steady effective flow of information during all project stages. Thereby, we guarantee competent responsiveness on all levels and manage your cell line and process development program accordingly.

Our satisfied loyal customers have repeatedly recommended Cellca’s CHO cell line development and upstream process development services to their peers, enabling continuous growth of our global customer base, which currently includes about 30 big and small pharma or biotech companies from Europe, the USA, Asia, and Australia with a customer retention rate of more than 80%. Industry references available on request.

Contact our experts to discuss our cell line development services today.

Contact us


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