Dr Stuart Knowling
Bioanalytical - Biacore
Dr Stuart Knowling joined Sartorius Stedim BioOutsource Limited in 2014 with over a decade of experience in biophysical protein and nucleic acid production and characterization, comprising both in vivo and in-vitro techniques. Following successful postdoctoral research appointments at both University College San Diego and the Scripps Research Institute, La Jolla; Dr Knowling has successfully adapted his knowledge of SPR and biophysical techniques to meeting the growing demands of the biosimilars market. Using SPR-based technologies, namely the Biacore T200 and Biacore 4000 systems, Stuart has initiated and developed multiple assay formats to characterize biosimilar monoclonal antibody-based therapies as part of larger similarity studies. Initially focused on the characterization of Fc binding characteristics, the Biacore department has expanded to offer solutions to the challenges that its clients meet in their biosimilar developments and to increase the range of SPR-based assays for biological characterization.