Tag: Early stage product development

The Importance of Accurate Determination of ADCC Activity During Biosimilar Development

19th August 2015

Category: Biosimilars

Tags: ,

By: Stefan Termen, Technical Services Scientist,

Cells infected with enveloped viruses will express viral proteins on their cell membranes, and many cancer cells will express specific surface antigens. These proteins are recognized by antibodies of the humoral immune system as targets for Antibody-Dependent Cell-mediated Cytotoxicity (ADCC). In this process, effector cells of the immune system recognize the bound antibodies through their More

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