Binding assays and immunoassays are typically employed to provide quantitative measurements of active substance or biomarkers, or to detect the presence of impurities in samples.
BioOutsource offers a variety of cost-effective, ready to use or customizable binding assays that can be applied across a range of scientific disciplines to support monoclonal antibody (mAb) development from early phase candidate selection to release of a marketed product. Our scientists will partner with you along the way to guarantee process success.
Binding Assays for Monoclonal Antibody Development
Our extensive experience in the development, optimization and validation of a wide range of binding assays and immunoassays helps take your mAb development process to the next level. All services are scalable, including a full offer of Good Clinical Practice (GCP), Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) testing services built to comply with European Medicines Agency (EMA) and US Food and Drug Administration (FDA) guidelines. We apply a range of cutting edge technologies to ensure we have a platform that suits developer needs.
The ready-to-use and custom services are detailed in the following pages, but we are always ready to partner to overcome your product characterization challenges.
- Fc Characterization (C1q, Fc-g Receptor, FcRn)
- Ready-to-use Surface Plasmon Resonance (SPR) with Biacore Assays
- SPR with Biacore Custom Assays
- Cell-based Binding Assays
- Custom Enzyme-Linked Immuno Assays (ELISA)
- Electrochemiluminescence (ECL) Custom Methods
- Mesoscale Discovery (MSD) Custom Assays
Measurement of Drug Substance/Product Function for mAbs
- Binding Interactions
- Ranking of Binding Affinity
- Receptor Binding Studies
- Detection of impurities
- Host Cell Protein (HCP) Assays
- Protein A
- Total protein
Contact our expert scientists today to discuss how our range of analytical services can improve your unique process.