FcRn Binding Assays

A key factor in the efficacy of therapeutic antibodies is the serum half-life and this is mostly determined by the interaction between the antibody and the FcRn. Evaluation and understanding of the ability to bind FcRn can play a pivotal role in developing a safe and efficacious molecule.

Flexible Anlytical Services

BioOutsource provides ready to use FcRn binding assays by SPR in a variety of orientations and pH’s using the Biacore T200, which is a versatile, label-free system with exceptional sensitivity. Our methods are extensively qualified using commercially available mAbs and we partner with you to verify or qualify your material for process success.

We also offer binding to the most common toxicology species FcRn to aid decision making and interpretation of your toxicology study. Cynomogolous monkey, rat, and mouse FcRn binding to human IgGs or fusion proteins can be demonstrated and compared with binding to human FcRn.

Contact our expert scientists today to discuss how our range of analytical services can improve your unique process.

BioOutsource FcRn Binding Assay Services

Sign-up to our newsletter to be the first to hear about our new services & offers

Sign-up to our newsletter to be the first to hear about our new services & offers

Enter your email address to subscribe to our newsletter which provides information about our services. By subscribing, you are agreeing to the processing of your personal information for this purpose as set out in our privacy policy