Webinar – The Next Level: Optimizations of a Platform for CHO Cell Line Generation

Register for our upcoming webinar on optimizing a platform for CHO cell line generation.

Date

Tuesday 30th October | 1pm GMT

Presenter

Cornelia Lindner, Team Lead Operations, Sartorius Stedim Cellca

Description

The market for therapeutic proteins is steadily growing and biological formats are getting more complex, resulting in a high demand for fast, reliable and efficient cell line and bioprocess development. This talk demonstrates how a CHO expression platform is improved in order to tackle and master these challenges. The presented developments comprise:

(i) Optimized expression vectors resulting in improved metabolic selection in the absence of selective agents (e.g. MTX, antibiotics), increased productivities and shortened timelines

(ii) Implementation of modern down-scale models (e.g. ambr 15 & ambr 250) for clone selection, process characterization and optimization

(iii) Process intensification leading to increased volumetric productivities and product titers > 10 g/L.

Click here to register for the webinar

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